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Sildenafil has been studied for high-altitude pulmonary edema (HAPE), but its use is currently not recommended for that indication. In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, indigestion, nasal congestion, and impaired vision, including photophobia and blurred vision.
- Sildenafil is also marketed as Viagra.
- It should be taken 30-60 minutes before activity.
- Avoid heavy meals close to taking sildenafil.
[4] Some sildenafil users have complained of seeing everything tinted blue (cyanopsia). [24] This cyanopsia can be explained because sildenafil, while selective for PDE5, does have some affinity for PDE6, which is the phosphodiesterase found in the retina.
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[8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal. [8] It also results in dilation of the blood vessels in the lungs. Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. [11] It was approved for medical use in the United States and in the European Union in 1998. [5][8][11][12] In 2023, it was the 151st most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Can Viagra cause a heart attack?
[13][14] It is available as a generic medication. [15][16] In the United Kingdom, it is available as a pharmacy medicine. The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete sexual intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for males with diabetes mellitus. Tentative evidence suggests that sildenafil may help males who experience antidepressant-induced erectile dysfunction.
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While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects. Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon;[9][21] these drugs have moderate efficacy for reducing the frequency and duration of sildenafil price ireland vasospastic episodes. [9] As of 2016,[update] their role more generally in Raynaud's was not clear. Sildenafil has shown some potential for improving exercise performance at high altitudes. However, its overall efficacy is not clear. Patients thus taking the drug may experience colorvision abnormalities.
| Storage Condition | Description | Importance |
|---|---|---|
| Temperature | Store below 30°C (86°F) | Preserves drug stability |
| Light Exposure | Keep in a dark place | Prevents degradation |
| Humidity | Keep dry, avoid moisture | Prevents quality deterioration |
| Container Type | Original container, tightly closed | Maintain potency |
Some complained of blurriness and loss of peripheral vision. In July 2005, the US Food and Drug Administration (FDA) updated labeling for tadalafil (Cialis), vardenafil (Levitra), and sildenafil (Viagra) to reflect a small number of post-marketing reports of sudden vision loss, while acknowledging that "...it is not possible to determine whether these oral medicines for erectile dysfunction were the cause of the loss of eyesight or whether the problem is related to other factors such as high blood pressure or diabetes, or to a combination of these problems. "[25] A careful review of pooled data from clinical trials containing well documented information about the dose and duration of exposure to the drug for a large number of patients, yields no evidence for an increased risk of non-arteritic anterior ischemic optic neuropathy or other adverse ocular events associated with PDE5 inhibitor use.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Kamagra | 100mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Viagra Generic | 25mg | 60 + 4 Pills | 71.99€ 68.56€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Viagra Generic | 100mg | 60 + 4 Pills | 96.36€ 91.77€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Viagra Generic | 25mg | 180 + 6 Pills | 154.93€ 147.55€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Kamagra | 100mg | 180 + 6 Pills | 436.79€ 415.99€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Generic | 150mg | 30 + 2 Pills | 72.32€ 68.88€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Kamagra Polo | 100mg | 32 Pills | 125.88€ 119.89€ | |
| Viagra Generic | 200mg | 30 + 2 Pills | 83.07€ 79.11€ |
Rare but serious adverse effects found through postmarketing surveillance include prolonged erections, severe low blood pressure, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. [4] In October 2007, the FDA announced that the labeling for all PDE5 inhibitors, including sildenafil, required a more prominent warning of the potential risk of sudden hearing loss.
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Consumer Information Use and Disclaimer This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine.
For more detailed information about sildenafil (Viagra), you can refer to the following sources:
This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication. This information should not be used to decide whether or not to take this medicine or any other medicine. I appreciate the fast delivery and the quality of the products. And a relief for meds I need to live.
What is ED (erectile dysfunction)?
Thank you for making this process so easy. The ordering process was straightforward and the customer service was excellent throughout. Everything arrived on time and as expected. A licensed provider checks your request within hours Fast, discreet shipping from our U.S.-based pharmacies What is TelyRx and how does it work? TelyRx.com is a digital platform that connects you with a provider allowing you to seek a prescription for medications via telehealth. Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection.
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Once you receive a prescription and the order is processed, TelyRx pharmacy delivers your medications directly to your doorstep through mail or courier services. What is TelyRx and how does it work? Is it safe to order medications online? Reputable pharmacies like TelyRx prioritize safety and adhere to strict quality standards. We connect you with a licensed healthcare professional to help you get a valid prescription.
How to tell if a man is using Viagra?
We verify the prescription and provider before we ship prescription medications. To minimize risk, we carry only non-controlled substances. Additionally, we have encrypted payment systems and maintain your privacy by protecting your personal information. How long does it take to receive my order? The delivery time will vary based on the shipping method you choose.
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We can get it there as soon as next day depending on when your sildenafil gel order is placed. We provide an estimated delivery time frame during the checkout process. How do I get prescribed a medication if my doctor is not in the TelyRx system? TelyRx offers a quick and easy way to obtain a prescription by using telehealth. Your doctor doesn't need to be in the TelyRx system. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects. Those using protease inhibitors are recommended to limit their use of sildenafil to no more than one 25 mg dose every 48 hours. [4] Other drugs that interfere with the metabolism of sildenafil include erythromycin and cimetidine, both of which can also lead to prolonged plasma half-life levels. The use of sildenafil and an α1 blocker (typically prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) at the same time may lead to low blood pressure, but this effect does not occur if they are taken at least 4 hours apart. Concomitant use of nitric oxide donors, organic nitrites and nitrates,[30] such as: nitroglycerinisosorbide mononitrateisosorbide dinitratesodium nitroprussidealkyl nitrites (commonly known as "poppers") Concomitant use of soluble guanylyl cyclase stimulators, such as riociguat Sildenafil should not be used if sexual activity is inadvisable due to underlying cardiovascular risk factors.
| Warning Point | Explanation | Advice |
|---|---|---|
| Overuse | Can lead to priapism (prolonged erection) | Seek medical attention immediately |
| Alcohol Interaction | Increases risk of side effects | Limit or avoid alcohol consumption |
| Recreational Use | Can cause unsafe situations | Use responsibly, under medical guidance |
Sildenafil's popularity with young adults has increased over the years.
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The providers who use our site review the information that you certify is accurate, and then, relying on that information write a prescription for medicine that helps with what you're going through, if they deem it appropriate to do so in their professional judgement. How can I transfer my prescription from my doctor? TelyRx provides patients with a telehealth service that allows a patient to receive a prescription upon approval from of the healthcare professionals that have partnered with us. We also offer the opportunity to for a physician to write a prescription through our platform so ask them to partner with us! If you have a paper prescription, it needs to be scanned and uploaded in the TelyRx system we will take the transfer from there.
How do I use the Viagra pill?
Sildenafil, sold under the brand name Viagra among others, sildenafil 100 mg tab is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8] It can be taken orally (swallowed by mouth), intravenously (injection into a vein), or through the sublingual route (dissolved under the tongue). [8][10] Onset when taken orally is typically within twenty minutes and lasts for about two hours.
Why do I need to know my blood pressure?
Common side effects include headaches, heartburn, and flushed skin. [8] Caution is advised in those with cardiovascular disease. [8] Rare but serious side effects include vision problems, hearing loss, and prolonged erection (priapism) that can lead to damage to the penis. [8] Sildenafil should not be taken by people on nitric oxide donors such as nitroglycerin, as this may result in a serious drop in blood pressure. Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [32] Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance,[33] or permanently increases penis size.
- Sildenafil is sometimes used off-label for pulmonary hypertension.
- Use with caution if you are on other blood pressure medications.
- Follow dosing instructions carefully to avoid complications.
